Generic Name: Methotrexate

Product Description

Methotrexate tablets are one of a of medicines called antimetabolites which affect cell growth, including the growth of cancer cells. Methotrexate Tablets can be used to treat severe cases of psoriasis (a skin disease) and rheumatoid arthritis (a disease of the joints). It is usually used for patients who have tried other treatments but their illness has not improved. It helps patients with psoriasis by killing the cells in the skin which are growing too quickly. It is these fast growing cells which cause the raised patches of skin in psoriasis. Important Information: Methotrexate will take 15 days to ship

Medication Name







2.5 mg

200 Tab.




2.5 mg

300 Tab.



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Prescription Methotrexate Drug Information

In the treatment of rheumatoid arthritis, Methotrexate Tablets is thought to stop or reduce inflammation in the joints by altering the body's defence mechanisms in the immune system. Methotrexate Tablets can also be used to treat several kinds of cancer when it can be given alone or in combination with other medicines. It is usually used in much higher doses when it is used to treat cancer and it will often be given as an injection rather than tablets. Do not take Methotrexate Tablets if you: - know that you are allergic to Methotrexate Tablets or any of the other ingredients in the tablets. - are pregnant, breastfeeding or trying for a baby, you and your partner should avoid conception (becoming pregnant or fathering children) for at least six months after your treatment with Methotrexate Tablets has stopped - suffer from a problem of excessive drinking (alcoholism) - have severe liver problems, including alcoholic liver disease and recent or active hepatitis (inflammation of the liver) - have severe kidney problems - have any serious blood disorders including severe anaemia or abnormal numbers of blood cells such as low white cells (leucopenia) or low small blood cell numbers (platelets) causing (thrombocytopenia) - have a medical condition or are receiving medication which lowers your resistance to infection - have symptoms which may suggest an active infectious disease (e.g. fever, chills, achiness) Even though some of the above may be obvious, it is important that your doctor is aware if any of them apply to you. Take special care and talk to your doctor or pharmacist before taking Methotrexate Tablets if you: - have any mild or moderate kidney problems or blood disorders - have stomach ulcers or suffer from inflammation and ulceration of the gut - have severe mouth ulcers - have diarrhoea - are weak or infirm - have excess fluid between the lungs and chest wall (pleural effusion) causing breathlessness or in the abdomen causing swelling of the stomach (ascites). These may affect the levels of Methotrexate Tablets in your blood - are receiving or intend to receive any vaccine, as Methotrexate Tablets can reduce their effect - have diabetes mellitus - are an elderly patient or a very young child - have impaired respiratory function - are receiving radiotherapy or ultraviolet (UV) radiation concurrently Patients with cancer Your doctor will decide the dose depending on your condition. Methotrexate Tablets may be the only drug given or it may be given with other drugs. Your doctor will want to monitor your progress, usually every 2-3 months, whilst you are receiving Methotrexate Tablets. Before, during and after your treatment you may have tests, such as a chest X-ray, physical examination and blood tests to check that your liver and kidneys are working properly. Do not miss your appointments as these are necessary to ensure that Methotrexate Tablets are used safely. Your doctor may give you additional medication to help make sure that Methotrexate Tablets does not collect in the kidneys. If you have taken an overdose of Methotrexate Tablets or more tablets than the doctor has told you to, you should get medical help immediately either by calling your doctor or by going to the nearest hospital casualty department. Always take the labelled medicine container with you, whether there are any Methotrexate Tablets left or not. If you forget to take Methotrexate Tablets Take it as soon as you remember if this is within two days. However, if you have missed a dose by more than two days, please contact your doctor for advice.

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